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​計畫主持人

劉浩澧 教授

劉浩澧博士在2003年取得國立臺灣大學電機工程博士學位。於2004-2005年期間，任職於美國波士頓哈佛大學醫學院/ Brigham & Womens Hospital放射科系擔任博士後研究員，從事治療超聲醫療儀器開發。於2005-2020年間任職於長庚大學電機系、並於2020年起加入國立台灣大學生醫資訊研究所。劉浩澧博士目前繼續研究治療用超音波之醫療器材技術開發，超音波輻照對血腦屏障（BBB）開啟進行大腦藥物輸送，超音波相位陣列設計等研究議題。劉博士在治療超音波領域發表了超過 120篇之SCI論文 （包含2篇被高引用論文）、 獲得超過40件全球專利。於2011及2018年，分別獲頒臺灣科技部吳大猷先生紀念獎、科技部傑出研究獎、及科技部傑出技轉貢獻獎。在國內。陸續榮獲電機工程學會優秀青年電機工程師獎及、永信李天德基金會青年醫藥科技奬、及有庠科技發明獎。在國際，曾榮獲國際超音波學會頒發Ferderic Lizzi Award，為第一位獲頒此獎之亞洲唯一學者。

Award

2020, The 7th Y. Z. Hsu Technology Invention Award (有庠科技發明獎)

2018, Acadamic Research Award, Ministry of Science and Technology (傑出研究獎)

2017, Future Technology Breakthrough Award, Ministry of Science and Technology (未來科技突破獎)

2017, Excellent Technology Transfer Award(傑出技轉貢獻獎), Ministry of Science and Technology, Taiwan..

2015, The 12th National Innovation Award (第12屆國家新創獎/「學研新創獎」類組).

2015, TienTe Lee Award (永信李天德醫藥科技獎/青年醫藥科技奬)

2013, Excellent Young Electrical Engineer Award (優秀青年電機工程師獎)

2013, Frederick Lizzi Early Career Award, by the International Society for Therapeutic Ultrasound (ISTU; 國際治療超音波學會).

2011, Wu Ta-You Memorial Award (吳大猷先生紀念獎), National Science Council, Taiwan.

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Publications

  1. ​H-L Liu, M-Y Hua, H-W Yang, C-Y Huang, P-C Chu, J-S Wua, I-C Tseng, J-J Wang, T-C Yen, P-Y Chen, and K-C Wei, “Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain,” Proceedings of National Academy of Science USA, Vol. 107, No. 34, pp.15205-15210, 2010 (IF=9.737, 4/56 in “Multidisciplinary sciences”).

  2. C-Y Lin, H-Y Hsieh, W.G. Pitt, C-Y Huang, I-C Tseng, C-K Yeh, K-C Wei, H-L Liu, “Focused ultrasound-induced blood-brain barrier opening for non-viral, non-invasive, and targeted gene delivery”, Journal of Controlled Release, 2015;212:1-9 (IF=7.705, 10/254 in “Pharmacology and Pharmacy”).

  3. AH Liao, HY Chou, YL Hsieh, SC Hsu, KC Wei, and HL Liu*, “Enhanced Therapeutic Epidermal growth factor receptor (EGFR) Antibody Delivery via Pulsed Ultrasound with Targeting Microbubbles for Glioma Treatment,” Journal of Medical and Biological Engineering, Vol. 1, pp. 1-9, Eng. DOI 10.1007/s40846-015-0032-9, 2014 (SCI IF = 0.971, 60/76 in “Engineering, Biomedical”).

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  • Dr. Liu has published over 130 SCI papers, over 40 worldwide patents been filed in areas of biomedical use of therapeutic ultrasound.

 

Principal Investigator

Hao-Li Liu, Ph.D., Professor

Hao-Li Liu received the Ph.D. degrees in Electrical Engineering in 2003 from the National Taiwan University, Taipei, Taiwan. In 2004-2005, He was the research fellow of the Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA. He is currently the Professor and the Director of Department of Electrical Engineering, Chang-Gung University, Taoyuan, Taiwan, and also the Adjunct Assistant Researcher of Division of Medical Engineering Research, National Health Research Institutes, Miaoli, Taiwan. Dr. Liu is currently continuing research in ultrasound thermal therapy and its treatment planning/ simulation, ultrasound-induced blood brain barrier (BBB) disruption for brain drug delivery, ultrasound phased array design. Dr. Liu has published over 130 SCI papers, over 40 worldwide patents been filed in areas of biomedical use of therapeutic ultrasound. He received the Distinguished Tech-Coop Award and the Distinguished Research Award from Chang-Gung University, respectively. Also in 2011, He received the Wu Ta-You Memorial Award from the National Science Council in Taiwan. In 2013, he received the Frederic Lizzi Award from the International Society for Therapeutic Ultrasound (ISTU) and also the Excellent Young Electrical Engineer Award from the Chinese Institute of Electrical Engineering to acknowledge his significant research contributions to therapeutic ultrasound. In 2015, as the first engineering-background honoree, Dr. Liu received the TienTe Lee Award to recognize his contribution on integrating medicine and engineering. In 2017 and 2018, he received the Academic Research Award from the Ministry of Science and Technology, Taiwan. Dr. Liu is a senior member of IEEE and previously served as the board member in the International Society of Therapeutic Ultrasound (ISTU) and Taiwan Association of Interventional & Therapeutic Ultrasound (TAITU).

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